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HEMATOPATHOLOGY CASES
Kenosha Pass, CO. 09/25/2016

Hematopathology Case Diagnosis

Case #

Clinical Information

Final Diagnosis

     
318 46 M. Multiple enlarged axillary lymph nodes Progressive transformation of germinal centers (PTGC) with increased IgG4+ cells
317 65 M. history of heart transplant. Inguinal lymphadenopathy

Trypanosoma cruzi infection in lymph node

316 71 M. enlarged inguinal lymph nodes Metallosis of Lymph node
315 39 M. HIV+, fever and systemic lymphadenopathy

Histoplasma Lymphadenitis

314 51 M. Multiple enlarged mesenteric lymph nodes Rosai-Dorfman disease
313 69 M. Cytopenia, renal failure and changed mental status. Skin biopsy Intravascular large B-cell lymphoma
312 37 M. HIV+, inguinal lymph node HIV lymphadenitis, burn-out phase

311

55 F. Fever, night sweats and systemic lymphadenopathy

Angioimmunoblastic T-cell lymphoma (AITL)

310

44 M. 2.7 cm right cervical mass

Lymphadenoma of parotid gland

309

59 M. 2.7 cm abdominal wall mass

Melanoma with immunoblastic morphology

308

54 M. Large left inguinal lymph node

B-cell lymphoma with DLBCL and classic Hodgkin lymphoma components

307

39 M. HIV+, several enlarged left inguinal lymph nodes

Kaposi sarcoma of lymph node

306

60 M. Pancytopenia and splenomegaly

Peripheral T-cell lymphoma, NOS, with gamma/delta T-cell derivation

305

74 F. Colon and small intestinal masses

EBV-associated high-grade transformation of mantle cell lymphoma

304

69 F. Bone lesion in the right femur

Plasma cell myeloma with t(11;14)

303

67 M. 3.1 cm skin lesion and right axillary lymphadenopathy

Blastic plasmacytoid dendritic cell neoplasm (BPDCN)

302

51 M. Fever, diarrhea and lymphadenopathy. Axillary lymph node

Whipple disease

301

9 M. Enlarge right tonsil

Pediatric follicular lymphoma

300

29 F. Right cervical lymphadenopathy

Kikuchi-Fujimoto lymphadenitis

299

74 M. Persistent leukocytosis and bone marrow biopsy

Atypical chronic myeloid leukemia (aCML) with CSF3R mutation

298

31 M. Cytopenia and splenomegaly. Bone marrow biopsy

Bone marrow with infiltration by hepatosplenic T-cell lymphoma

297

61 F. Bone marrow biopsy

Metastatic angioimmunoblastic T-cell lymphoma

296

68 F. Macrocytosis and neutropenia. Bone marrow biopsy

Myelodysplastic syndrome with 5q deletion

295

86 F. Bone marrow biopsy

Acute myeloid leukemia, blasts mimicking promyelocytes

294

39 M. Left cervical lymphadenopathy

Metastatic nasopharyngeal carcinoma with sinusoidal infiltrative pattern

293

35 M. Pancytopenia and bone marrow biopsy

Acute myeloid leukemia with t(15;17)

292

53 M. Bone marrow biopsy

Metastatic classic Hodgkin lymphoma

291

66 F. Macrocytosis and neutropenia. Bone marrow biopsy

Myelodysplastic syndrome with 5q deletion

290

63 F. Pancytopenia and bone marrow biopsy

Acute Myeloid Leukemia with extensive necrosis and Charcot-Leyden crystals

289

21 M. Anemia and bone marrow biopsy

Megaloblastic Anemia, Mimicking Microangiopathic Hemolytic Anemia

288

68 F. Bone marrow biopsy

Markedly left shift granulopoiesis, mimicking AML

287

71 M. Inguinal lymph node

Metastatic melanoma, mimicking histiocytic lesion or lymphoma

286

24 F. Cervical lymphadenopathy

Kikuchi-Fujimoto lymphadenitis

285

31 F. Cervical lymphadenopathy

Kikuchi-Fujimoto lymphadenitis

284

24 F. Cervical lymphadenopathy

Kikuchi-Fujimoto lymphadenitis

283

72 F. Cytopenia and bone marrow biopsy

Megaloblastic Anemia

282

53 F. An incidental splenic mass

Inflammatory Pseudotumor-like Follicular Dendritic Cell Tumor

281

64 F. Bone marrow biopsy

Acute myeloid leukemia with inv(3)(q21q26.2)

280.

68 F. Anemia with MCV 112. Peripheral blood smear

Megaloblastic Anemia

279.

37 M. History of thalassemia. Peripheral blood smear

Basophilic stippling

278.

23 M. Peripheral blood smear.

Hb C Disease (HbCC)

277.

27 M. Peripheral blood smear

Hb SC

276.

16 M. Peripheral blood smear

Sickle Cell Disease (HbSS)

275.

75 M. Peripheral blood smear

Iron Deficiency Anemia

274.

48 F. Serum monoclonal IgM = 5.6g. Bone marrow biopsy

Lymphoplasmacytic Lymphoma / Waldenström's Macroglobulinemia

273.

76 M. Fever for 6 days. Peripheral blood smear

Histoplasmosis

272.

64 F. Bone marrow biopsy

AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.1)

271.

65 F. Bone marrow biopsy

Markedly Left-Shifted Granulopoiesis

270.

66 F. Bone marrow biopsy

AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.1)

269.

65 M. Inguinal lymph node

Small Lymphocytic Lymphoma with Herpes Simplex Virus Infection

268.

13 M. Peripheral blood smear

Sickle Cell Disease

267.

62 M. Recently onset of pneumonia. Peripheral blood smear

Cold Agglutination

266.

18 M. Peripheral blood smear

May-Hegglin Anomaly

265.

11 M. Peripheral blood smear

Hereditary Spherocytosis

264.

21 M. Peripheral blood smear

Chediak-Higashi Syndrome

263.

61 M. Pancytopenia. Bone marrow biopsy

Auer rods in AML

262.

73 M. Pancytopenia, monoclonal gammopathy. Bone marrow biopsy

Plasma cell myeloma with lymphoid appearance

261.

68 F. Pancytopenia. Bone marrow biopsy

Trilineage dysplasia in MDS

260.

45 M. Multiple skin lesions

T-Cell Prolymphocytic Leukemia with Skin Involvement

259.

55 M. Bone marrow biopsy for routine follow-up of transplant

Mycobacterial Granuloma in Bone Marrow

258.

58 M. Pancytopenia. Bone marrow biopsy

Erythroid Megaloblastoid Changes in MDS

257.

76 F. Anemia. Bone marrow biopsy

Megaloblastic Anemia

256.

67 M. Axillary lymph node

Blastoid Mantle Cell Lymphoma Transformed from Classic Mantle Cell Lymphoma

255.

84 F. A mass within the left low lobe of lung

Lymphoplasmacytic Lymphoma / Waldenström's Macroglobulinemia

254.

33 M. Axillary lymph node

Anaplastic Large Cell Lymphoma, ALK+

253.

34 M. 3rd degree burn. Peripheral blood smear

Thermal Injury

252.

57 M. Marked leukocytosis. Bone marrow biopsy

Chronic Myelogenous Leukemia

251.

44 F. Cervical lymph node

Classic Hodgkin Lymphoma, Lymphocyte Depletion Subtype

250.

45 F. A large cervical lymph node

Follicular  Dendritic Cell Sarcoma

249.

52 M. A large inguinal lymph node

Interdigitating Dendritic Cell Sarcoma

248.

43 M. An abdominal wall soft tissue mass

Rosai-Dorfman Disease of Soft Tissue

247.

55 F. A dura based brain lesion

Histiocytic Sarcoma

246.

3 M. Cytopenia and hepatosplenomegaly. Bone marrow biopsy

Gaucher Disease

245.

16 M. A large cervical lymph node

Metastatic Undifferentiated Nasopharyngeal Carcinoma

244.

45 M. A large cervical lymph node

Classic Hodgkin Lymphoma, Syncitial Variant

243.

38 M. Peripheral blood smear

Acute myeloid leukemia with t(15;17)

242.

63 M. A 6.0cm inguinal lymph node

Nodal Merkel Cell Carcinoma

241.

46 F. Pancytopenia. Bone marrow biopsy

Metastatic lobular carcinoma of breast in bone marrow

240.

47 M. Excisional skin biopsy

Granulomatous mycosis fungoides

239.

57 M. Lymphadenopathy. Bone marrow biopsy

Diffuse Large B-Cell Lymphoma Involving Bone Marrow

238.

32 F. Bone marrow biopsy

Acute Myeloid Leukemia With Inv16 or t(16;16)

237.

49 F. Biopsy of breast implant capsule

Implant-related primary anaplastic large cell lymphoma (ALCL) of the breast

236.

55 M. Bone marrow biopsy

Plasma Cell Myeloma

235.

61 M. Bone marrow biopsy

Acute Myeloid Leukemia with t(8;21)(q22;q22)

234.

62 M. History of skin lesion. Bone marrow biopsy

Blastic Plasmacytoid Dendritic Cell Neoplasm

233.

37 M. Lymphadenopathy. Bone marrow biopsy

Bone marrow involvement by anaplastic large cell lymphoma

232.

34 M. Bone marrow biopsy

Acute Myeloid Leukemia With Inv16 or t(16;16)

231.

49 F. A 2.7 cm breast mass lesion

Plasmacytoma of breast

230.

35 F. A 3.3 cm cervical lymph node

Classic Hodgkin Lymphoma, Mixed Cellularity Type, Histiocyte-Rich Variant

229.

61 M. An enlarged inguinal lymph node

Peripheral T-Cell lymphoma, Lymphoepithelioid Variant (Lennert Lymphoma)

228.

53 F. Large cervical lymph node.

Follicular Lymphoma with Signet-Ring Tumor cells

227.

11 M. A 4 cm cecal mass.

Burkitt Lymphoma

226.

43 M. Inguinal lymph nodes

Follicular Lymphoma with Sclerosis

225.

18 M. Cervical lymph node biopsy

Classic Hodgkin Lymphoma, Mixed Cellularity Type

224.

69 F. Marked macrocytic anemia. Bone marrow biopsy

Megaloblastic Anemia

223.

48 F. Bone marrow biopsy

Plasma Cell Myeloma

222.

61 F. Enlarged inguinal lymph node

Follicular Lymphoma with Marginal Zone Differentiation

221.

56 M. Bone marrow biopsy

Plasma Cell Myeloma  with Intracytoplasmic Crystals

220.

15 M. Atypical cells in the peripheral blood smear

B-Cell Acute Lymphoblastic Leukemia

219.

56 M. Bone marrow biopsy

Plasma Cell Myeloma

218.

42 M. Right axillary lymphadenopathy

Nodular Lymphocyte Predominant Hodgkin Lymphoma

217.

69 M. Pancytopenia and splenomegaly. Bone marrow biopsy

Hairy Cell Leukemia

216.

61 F. Marked lymphocytosis and splenomegaly. Bone marrow biopsy

B-Cell Prolymphocytic Leukemia

215.

34 F. Cervical lymphadenopathy

Anaplastic Large Cell Lymphoma

214.

81 M. Marked leukocytosis. Blood smear

Chronic lymphocytic Leukemia

213.

43 F. Axillary lymph nodes

Plasmacytoid dendritic cell nodule

212.

52 F. Lymphadenopathy and leukocytosis. Blood smear

Circulating Follicular Lymphoma Cells in Peripheral Blood

211.

59 M. Peripheral blood smear

Circulating Sezary Cells in Peripheral Blood

210.

68 M. Peripheral blood smear

Circulating Sezary Cells in Peripheral Blood

209.

71 F. Lymphadenopathy and leukocytosis. Blood smear

Circulating Mantle Cell Lymphoma Cells in Peripheral Blood

208.

66 M. Leukocytosis, hepatosplenomegaly, and lymphadenopathy

T-Cell Prolymphocytic Leukemia (T-PLL)

207.

65 M. Peripheral blood smear

Plasma Cell Leukemia

206.

49 F. Systemic lymphadenopathy and leukocytosis. Blood smear

Circulating Follicular Lymphoma Cells in Peripheral Blood

205.

71 M. Bone marrow biopsy

Plasma Cell Myeloma

204.

66 M. Bone marrow biopsy

Plasma Cell Myeloma

203.

59 F. Lymphadenopathy. Bone marrow biopsy

Classic Hodgkin Lymphoma Involving Bone Marrow

202.

41 M. A humerus bone lesion

Langerhans Cell Histiocytosis

201.

74 M. Leukocytosis, hepatosplenomegaly, and lymphadenopathy

T-Cell Prolymphocytic Leukemia (T-PLL)

200.

54 M. HIV+, systemic lymphadenopathy

Castleman disease, multicentric

199.

9 M. Fever and sore throat with enlarged bilateral tonsils

Acute infectious mononucleosis of tonsils

198.

13 M. An enlarge cervical lymph node

Kimura disease, nodal

197.

37 F. Cervical lymph node

Systemic lupus erythematosus (SLE) lymphadenopathy

196.

39 F. An enlarged left cervical lymph node

Kikuchi-Fujimoto lymphadenitis

195.

29 F. Cervical lymphadenopathy

Toxoplasmosis lymphadenopathy

194.

64 M. Skin lesion on the back

Classic Hodgkin lymphoma, primary cutaneous

193.

46 F. A lip mucosal nodule

Extranodal marginal zone lymphoma, MALT type

192.

60 F. An enlarged cervical lymph node

Systemic mastocytosis involving lymph node

191.

34 M. An enlarged inguinal lymph node

Anaplastic large cell lymphoma, nodal

190.

41 F. Multiple skin lesions

Systemic mastocytosis

189.

67 M. Lung lesions

Lymphomatoid granulomatosis of lung

188.

73 M. Cervical lymphadenopathy

Plasma Cell Myeloma Involving Lymph Node

187.

68 M. Splenomegaly

Plasma Cell Myeloma Involving Spleen

186.

1-year-old male. Pancytopenia and hepatosplenomegaly

Niemann-Pick Disease

185.

41 M. HIV+, oral lesion

Plasmablastic Lymphoma of Oral Cavity

184.

61 M. Brain lesion

Primary CNS lymphoma

183.

56 F. Pathologic fracture of the femur

Rosai-Dorfman Disease of Bone

182.

58 M. Obturator lymph nodes

Metallosis of Lymph node

181.

38 M. Soft tissue mass of chest wall

Rosai-Dorfman Disease

180.

72 M. Mediastinal lymph node biopsy and bone marrow biopsy

ALK Positive Large B-Cell Lymphoma

179.

67 F. Mesenteric lymphadenopathy with colonic mass lesions

Sinusoidal CD30+ Large B-Cell Lymphoma

178.

52 M. Multiple enlarge cervical lymph nodes

Classic Hodgkin Lymphoma, Mixed Cellularity Subtype

177.

72 M. Blood clots from  a dissecting aortic aneurysm

Diffuse large B-cell lymphoma

176.

47 M. Mesenteric lymphadenopathy

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

175.

56 F. A cecal polyp with mesenteric lymphadenopathy

Diffuse large B-cell lymphoma

174.

49 F. History of breast implant. A breast mass

Metastatic Melanoma

173.

61 M. Bone marrow biopsy

Systemic mastocytosis

172.

42 F. Cervical lymphadenopathy

Classic Hodgkin Lymphoma, Lymphocyte Depletion Type

171.

46 F. Cervical lymphadenopathy

Metastatic Thyroid Medullary Carcinoma

170.

34 M. HIV+, gastric lesion and systemic lymphadenopathy

Large B-cell lymphoma

169.

36 M. HIV+, inguinal lymphadenopathy

Vascular proliferation

168.

56 F. Ovarian mass

Diffuse large B-cell lymphoma

167.

47 F. Anterior mediastinal mass

Classic Hodgkin Lymphoma in Lymphoepithelial Cyst

166.

65 M. Neck abscess and cervical lymphadenopathy

Necrotizing granulomas

165.

66 F. Axillary lymph node dissection for breast carcinoma

Mantle Zone Hyperplasia

164.

56 F. Colectomy for Crohn's disease. Mesenteric lymph nodes

Granulomas in lymph node

163.

74 M. Multiple enlarged cervical lymph nodes

SLL with large B-cell transformation and metastatic squamous cell carcinoma

162.

17 M. Cervical lymphadenopathy

Rosai-Dorfman disease

161.

55 F. Axillary lymph node dissection for breast carcinoma

Benign Mammary Glandular Inclusions in Lymph Node

160.

16 M. HIV+. Cervical lymphadenopathy

Extracavitary HHV8 associated large B-cell lymphoma

159.

44 F. Axillary lymphadenopathy

Metastatic lobular carcinoma of breast in lymph node

158.

44 F. A cystic lesion in the spleen

?

157.

39 M. Splenectomy due to trauma

Marginal Zone Hyperplasia

156.

34 M. Splenectomy due to trauma

Amyloidosis of Spleen

155.

24 F. Axillary lymph node dissection for breast cancer

Mantle zone hyperplasia of lymph node

154.

45 M. Brain lesion

Myeloid sarcoma in brain

153.

5-hour-old neonate. Abnormal CBC and peripheral blood smear

Transient Abnormal Myelopoiesis (TAM) of neonate

152.

23 M. Enlarged cervical lymph nodes

Atrophy of Lymph Node due to Sickle Cell Disease

151.

39 F. Splenomegaly (2,568 grams) and lymphadenopathy

Extramedullary Hematopoiesis

150.

55 F. Axillary lymphadenopathy.

Metastatic Lobular Carcinoma of Breast

149.

45 F. Incidental finding in axillary lymph node

Intranodal melanocytic nevocellular inclusions (nodal nevi)

148.

37 M. HIV+. Colon lesion and mesenteric lymphadenopathy

Extracavitary HHV8 associated large B-cell lymphoma

147.

59 F. Cervical lymphadenopathy

Atypical lymphohistiocytic proliferation

146.

28 M. Nasal lesion

Nasal NK/T cell lymphoma

145.

33 F. A 3.9 cm periportal lymph node

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

144.

66 F. A 3.2 × 3.0 cm right axillary lymph node

Castleman disease, hyaline vascular type

143.

30 M. HIV+. Generalized lymphadenopathy

HIV lymphadenitis, chronic phase

142.

27 M. HIV+. Generalized lymphadenopathy

HIV lymphadenitis, acute phase

141.

62 M. An enlarged obturator lymph node

Metallosis of lymph node

140.

61 m. Cervical lymphadenopathy

Myeloid sarcoma involving lymph node

139.

53 M. Inguinal lymphadenopathy

Marginal zone lymphoma with follicular colonization

138.

51 F. Thyroid lesion

Diffuse large B-cell lymphoma of thyroid

137.

60 F. Splenomegaly and lymphadenopathy

Mantle cell lymphoma

136.

36 F. Inguinal lymphadenopathy

Peripheral T-cell lymphoma involving lymph node

135.

45 F. Axillary lymphadenopathy

Peripheral T-cell lymphoma involving lymph node

134.

45 F. Multiple nodular lesions in spleen

Littoral cell hemangioma

133.

32 M. HIV+, cervical lymphadenopathy

Mycobacterium avium complex (MAC)

132.

45 M. Severe anemia and leukopenia. Bone marrow biopsy

Marrow changes in copper deficiency 

131.

64 M. Peripheral blood smear

Plasma Cell Leukemia, IgA type, with Flame Cells

130.

37 M. Soft tissue mass in arm

Kimura Disease

129.

24 M. Cervical lymphadenopathy and splenomegaly

Lymphadenopathy associated with infectious mononucleosis

128.

80 F. Orbital mass

Mantle Cell Lymphoma

127.

47 F. Axillary lymphadenopathy

Peipheral T-cell lymphoma involving lymph node

126.

33 F. Inguinal lymphadenopathy

Cat scratch disease of lymph node

125.

28 F. Axillary lymphadenopathy

Cat scratch disease of lymph node

124.

77 M. Severe anemia. Bone marrow biopsy

Parvovirus infection of erythroid cells in bone marrow

123.

5 M. Ocular lesion

Myeloid sarcoma, monoblastic

122.

56 F. Multiple skin lesions

NK/T cell lymphoma v.s. blastic plasmacytoid dendritic cell neoplasm

121.

48 M. Cervical lymphadenopathy

Peripheral T-Cell lymphoma, Lymphoepithelioid Variant (Lennert Lymphoma)

120.

45 F. Bone marrow biopsy

Systemic mastocytosis

119.

51 F. Enlarged inguinal lymph node

Palisaded Myofibroblastoma

118.

58 M. Proximal humerus bone lesion

Large B-cell lymphoma

117.

37 F. Enlarged cervical lymph node

Anaplastic large cell lymphoma, ALK1+

116.

46 F. Multiple skin lesions

Primary Cutaneous CD30+ Lymphoproliferative Disorder

115.

46 F. Bilateral cervical lymphadenopathy

Toxoplasma lymphadenitis

114.

58 M. Testicular mass

Large B-cell lymphoma

113.

55 F. Enlarged submandibular lymph node

Large B-cell lymphoma

112.

66 M. Renal mass

Follicular lymphoma

111.

62 M. BCG treatment for urothelial carcinoma. Bone marrow biopsy

BCG Granuloma in Bone Marrow

110.

65 F. Scalp skin lesion

Follicular lymphoma, primary or metastatic

109.

65 F. Cervical lymphadenopathy

Alveolar rhabdomyosarcoma, metastatic 

108.

65 M. History of CLL with anemia and fever. Bone marrow biopsy.

Histoplasmosis

107.

63 M. Peripheral blood smear and CSF

Mantle Cell Lymphoma

106.

68 F. Massive splenomegaly

Splenic Marginal Zone Lymphoma

105.

37 M. Hepatosplenomegaly

Hepatosplenic Gamma-Delta T-Cell Lymphoma 

104.

63 M. Gastric biopsy

Mantle Cell Lymphoma

103.

9 M. Cervical lymphadenopathy

Rosai-Dorfman Disease

102.

45 M. Testicular mass

Rosai-Dorfman Disease

101.

56 M. Pancytopenia and bone pain. Bone marrow biopsy

Burkitt Lymphoma

100.

75 M. Systemic lymphadenopathy and multiple organ involvement

Classic Hodgkin Lymphoma

99.

3 M. An ileocecal mass

Burkitt lymphoma

98.

5 M. A cecal mass and enlarged mesenteric lymph nodes

Burkitt lymphoma

97.

4 F. Bone marrow biopsy

Metastatic neuroblastoma in the bone marrow

96.

10 M. Splenomegaly, thrombocytopenia and leukopenia

Gaucher's disease in bone marrow

95.

7 M. A large mediastinal mass

T-cell lymphoblastic lymphoma

94.

5 weeks old female. Abnormal CBC and blood smear

Acute megakaryoblastic leukemia with t(1;22)

93.

16 F. Atypical lymphocytosis of peripheral blood

Infectious mononucleosis

92.

6 F. An enlarged left neck lymph node

T-cell lymphoblastic lymphoma

91.

4 M. Enlarged mesenteric lymph nodes

Burkitt lymphoma

90.

16 F. An enlarged left postauricular lymph node

Anaplastic large cell lymphoma, lymphohistiocytic variant

89.

11 F. A mass in the occipital skull

Langerhans cell histiocytosis

88.

61 M. Right cervical lymph nodes

Small lymphocytic lymphoma

87.

67 M. Atypical lymphocytosis in peripheral blood

Mantle cell lymphoma cells in peripheral blood

86.

41 F. HIV+ with abdominal lymphadenopathy

Castleman disease

85.

57 M. Axillary lymphadenopathy

Marginal zone lymphoma, primary nodal

84.

44 M. Axillary lymphadenopathy

Lymphadenopathy associated with tattoo

83.

65 M. Colon mass

Diffuse Large B-cell lymphoma of the colon

82.

65 M. Splenomegaly and lymphadenopathy

Myeloid sarcoma in lymph node

81.

65 M. Bone marrow biopsy

Acute myeloid leukemia

80.

66 M. Bilateral inguinal lymphadenopathy

Diffuse large B-cell lymphoma, transformed from follicular lymphoma

79.

65 M. HIV+ and left inguinal lymphadenopathy

Myeloid sarcoma in lymph node

78.

75 M. A T5 epidural mass

Diffuse large B-cell lymphoma

77.

45 M. A 5 cm pancreatic mass

Myeloid sarcoma of pancreas

76.

58 M. Cervical lymph node

Classic Hodgkin lymphoma

75.

62 F. Minor salivary gland lesion

Extranodal marginal zone lymphoma (MALT Lymphoma)

74.

65 M. Inguinal lymph node

Mantle cell lymphoma

73.

70 M. Inguinal lymph node

Merkel cell carcinoma of lymph node

72.

69 F. Skin lesion

Primary cutaneous follicle center lymphoma

71.

56 M. Rectal mass

Mantle cell lymphoma

70.

66 M, h/o CLL/SLL. Cervical lymph node

Diffuse large B-cell lymphoma transformed from CLL (Richter’s transformation)

69.

27 F. Cervical lymph node

Classic Hodgkin Lymphoma, nodular sclerosis type, syncitial variant

68.

27 M. Inguinal lymph node

Nodular lymphocyte predominant Hodgkin lymphoma

67.

61 F. Bone marrow

Systemic mastocytosis

66.

50 M. Serum protein electrophoresis

Light chain myeloma

65.

39 M. Bone marrow

Metastatic angiosarcoma to the bone marrow

64.

18 F, h/o anemia and splenomegaly. Peripheral blood smear

β-Thalassemia

63.

17 M, anemia. Peripheral blood smear

Hereditary elliptocytosis

62.

11 M, soft tissue mass from right upper arm

Kimura disease

61.

62 M, a small intestinal mass

Follicular lymphoma, low grade

60.

58 F, right axillary lymph node

Diffuse large B-cell lymphoma

59.

59 F, left axillary lymph node

Angioimmunoblastic T-cell lymphoma

58.

80 F, right axillary lymph node

Metastatic desmoplastic melanoma

57.

28 F, right medial thigh skin lesion

Cutaneous mastocytosis

56.

37 F, right neck lymph node

Classic Hodgkin lymphoma, nodular sclerosis subtype

55.

24 F, an incidental anterior mediastinal mass

Castleman disease, hyaline vascular subtype

54.

38 F, liver lesion

Systemic mastocytosis

53.

54 M, inguinal lymph node

Peripheral T-cell lymphoma, nodal

52.

72 M, a small intestinal mass

Extra nodal marginal zone lymphoma

51.

47 F, history of Castleman disease. Mediastinal lymph node

Follicular dendritic cell sarcoma

50.

68 M, a solitary cutaneous nodule

Primary cutaneous anaplastic large cell lymphoma

49.

39 F, gallbladder

Systemic mastocytosis

48.

57 F, enlarged mesenteric lymph nodes

Diffuse large B-cell lymphoma, CD30+

47.

33 M, subcutaneous soft tissue mass

Anaplastic large cell lymphoma, small cell variant

46.

44 F, generalized lymphadenopathy. Cervical lymph node

Sarcoidosis and asteroid body

45.

43 F, marked leukocytosis. Peripheral blood smear

Acute myeloid leukemia

44.

49 F, history of splenectomy. Peripheral blood smear

Basophilic stippling and Howell-Jolly bodies

43.

77 M, left supraclavicular lymph node

Granular cell sarcoma (Myeloid sarcoma)

42.

58 M, history of CLL and gastroesophageal mass. Bone marrow

Plasmablastic lymphoma directly transformed from CLL/SLL

41.

58 M, history of CLL. Gastroesophageal mass

Plasmablastic lymphoma directly transformed from CLL/SLL

40.

45 F, history of splenectomy. Peripheral blood

Howell-Jolly bodies

39.

50 F, left cervical lymph node

Classic Hodgkin lymphoma, nodular sclerosis subtype

38.

29 M, right submandibular lymph node

Nodular lymphocyte predominant Hodgkin lymphoma

37.

18 F, right thyroid lesion

Classic Hodgkin lymphoma, nodular sclerosis subtype

36.

58 M, right axillary lymph node

Chronic lymphocytic leukemia/small lymphocytic lymphoma

35.

60 M, retroperitoneal lymph node

Nodal marginal zone lymphoma

34.

66 M, right testicular mass

Primary testicular large B-cell lymphoma

33.

56 M, mediastinal lymph node

Follicular lymphoma

32.

80 F, right axillary lymph node

Angioimmunoblastic T-cell lymphoma

31.

15 M, anemia and abnormal RBC shapes. Peripheral blood

Hereditary elliptocytosis

30.

63 M, lymphocytosis

Large granular lymphocytic leukemia

29.

59 M, nasal mass biopsy

Diffuse large B-cell lymphoma of nasal cavity

28.

53 M, splenomegaly

Diffuse large B-cell lymphoma of spleen

27.

58 M, skin lesions and systemic lymphadenopathy.

Anaplastic large cell lymphoma, ALK-, involving lymph node and skin

26.

74 M, pancytopenia. Bone marrow biopsy

Metastatic prostatic carcinoma

25.

11 M, axillary lymph node

Anaplastic large cell lymphoma, ALK+, lymphohistiocytic variant

24.

44 M. Bone marrow biopsy

Acute myeloid leukemia

23.

54 M. Bone marrow biopsy

Acute promyelocytic leukemia, hypergranular type

22.

55 M, small intestine mass

Entropathy-associated T-cell lymphoma (EATL), type II

21.

47 M, left inguinal lymph node

Mantle cell lymphoma

20.

71 M, inguinal lymph node

Anaplastic Large Cell Lymphoma, ALK-

19.

11 M, marked leukocytosis. Peripheral blood

Acute myeloid leukemia with monocytic differentiation

18.

81 M, multiple lytic bone lesions. Bone marrow biopsy

Plasma cell myeloma, with plasmablastic features

17.

73 M, h/o myelodysplasia. Peripheral blood

Chronic myelomonocytic leukemia (CMML)

16.

48 F, vulva lesion

Langerhans cell histiocytosis of the vulva

15.

52 M, h/o CLL, splenic hilar lymph node

Hodgkin lymphoma, transformed from CLL/SLL, Richter’s transformation

14.

39 M, supraclavicular lymph node

Nodular lymphocyte predominant Hodgkin lymphoma

13.

78 M, leukocytosis. Bone marrow biopsy

Acute myeloid leukemia with monocytic differentiation and t(8;22)

12.

57 M, multiple small colonic polyps

Mantle cell lymphoma, presented as lymphomatoid polyposis

11.

36 M, inguinal lymph node

Anaplastic Large Cell Lymphoma, ALK-

10.

52 M, severe anemia. Bone marrow biopsy

Myelodysplastic syndrome with t(3;9)(q22;p24)

9.

67 F, marked lymphocytosis and splenomegaly. Peripheral blood

B-cell prolymphocytic leukemia

8.

66 M, lymphocytosis. Peripheral blood

Chronic lymphocytic leukemia

7.

32 F, Fever, superficial lymphadenopathy

Kikuchi-Fujimoto lymphadenitis (histiocytic necrotizing lymphadenitis)

6.

56 M, h/o CML. Bone marrow biopsy

Acute lymphoblastic leukemia, transformed from CML

5.

77 M, h/o MGUS. Bone marrow biopsy

Plasma cell myeloma

4.

24 M, pancytopenia. Bone marrow biopsy

Acute promyelocytic leukemia, hypergranular type

3.

51 F, right cervical lymphadenopathy

Classic Hodgkin lymphoma, lymphocyte-rich subtype, nodular variant

2.

49 M, leukocytosis. Bone marrow biopsy

Acute promyelocytic leukemia, hypogranular type

1.

51 F, SLE and anemia. Bone marrow biopsy

Lupus Erythematosus cell (LE Cell)